Are you a student? https://www.perrinemeteyer.com/china-medical-journal-english-b321.pdf medical journal english  By subsite of colorectal cancer, splenic flexure was associated with a 3.35-fold increased risk (95% CI 2.83-3.94) for second primary colorectal cancer. They added that "SIRs declined with increasing anatomic distance from the splenic flexure."